The morgue’s contract with Michigan Medicine expires in September, and the two sides are currently in talks to renew it. The case is now closed, but it leaves many with an uneasy feeling about what other mistakes might have been made at Knollwood Memorial Park. While some issues at the morgue happened under the guidance of Michigan Medicine, this one did not. Repaired a backup generator transfer switch and are evaluating replacement refrigeration equipment Michigan Medicine Launched a project with the U-M College of Engineering to assess morgue systems and procedures We are strongly committed to continuously improving our services, and have made some recent progress:Ĭreated a new position of identification coordinator, interviews underwayīuilt a prototype of public facing web-based portal to get public participation in helping identify missing persons, currently under review Although the misidentification occurred prior to Michigan Medicine operating the morgue, we regret the mistakes made in this case and are committed to maintaining higher standards of care and practice. Many of those steps - including checking dental, radiology and anthropology records – are standard parts of the Wayne County Morgue’s process. The body of Steven Wetter was misidentified after his death in 2011, after some critical steps were not taken by morgue officials involved. Michigan Medicine, which gets paid about $6 million per year to run the Wayne County Morgue, issued the following statement: he is running that,” Genelle Allen said.Īllen said the county is concerned and disturbed by all the problems that have been uncovered at the morgue. “Well, I will say that you’re right that the buck stops at the top and. The chief operating officer of Wayne County, who oversees the morgue, spoke about how the facility was run under Schmidt’s leadership. Carl Schmidt, is keeping quiet about the case and wouldn’t talk to Local 4 about this investigation. The report showed there were “no signs of trauma or foul play.”ĭocuments obtained by the Defenders show that originally, the Wayne County Medical Examiner’s Office thought the body was that of a female, but wrote that “identification was very difficult.” At the time, there was a house on the lot, and inside, police found a decomposing body, according to records. Two years earlier, in 2011, a tip to Crime Stoppers led police to a lot in the 16000 block of Hazelton Street on Detroit’s west side. 11-851, but why was an exhumation needed? In 2013, there was a dig at Knollwood Memorial Park in Canton Township that many authorities don’t want to talk about. But in reality, it was a man, and the woman is alive and well. Now, Defender Karen Drew has learned about another mistake: A body was buried, and the person identified as a woman. These results show the therapeutic potential of this novel cell cycle inhibitor and support clinical evaluation of JNJ-7706621.The Defenders have been exposing these mistakes in the hope that it will bring change, hold people accountable and get some answers for affected families. There was a direct correlation between total cumulative dose given and antitumor effect regardless of the dosing schedule. In a human tumor xenograft model, several intermittent dosing schedules were identified that produced significant antitumor activity. Additional cellular effects due to inhibition of Aurora kinases included endoreduplication and inhibition of histone H3 phosphorylation. ![]() Flow cytometric analysis of DNA content showed that JNJ-7706621 delayed progression through G1 and arrested the cell cycle at the G2-M phase. Inhibition of CDK1 kinase activity, altered CDK1 phosphorylation status, and interference with downstream substrates such as retinoblastoma were also shown in human tumor cells following drug treatment. At low concentrations, JNJ-7706621 slowed the growth of cells and at higher concentrations induced cytotoxicity. In human cancer cells, treatment with JNJ-7706621 inhibited cell growth independent of p53, retinoblastoma, or P-glycoprotein status activated apoptosis and reduced colony formation. JNJ-7706621 is a novel cell cycle inhibitor that showed potent inhibition of several cyclin-dependent kinases (CDK) and Aurora kinases and selectively blocked proliferation of tumor cells of various origins but was about 10-fold less effective at inhibiting normal human cell growth in vitro. Modulation of aberrant cell cycle regulation is a potential therapeutic strategy applicable to a wide range of tumor types.
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